Glucose-activated RUNX2 phosphorylation
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Adam D. Pierce; Ian E. Anglin; Michele I. Vitolo; Maria T. Mochin; Karen F. Unde
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Article
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2011
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John Wiley and Sons
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English
β 564 KB
## Abstract The runtβrelated proteinβ2 (RUNX2) is a DNAβbinding transcription factor that regulates bone formation, tumor cell metastasis, endothelial cell (EC) proliferation, and angiogenesis. RUNX2 DNA binding is glucose and cell cycle regulated. We propose that glucose may activate RUNX2 through