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Serotonin 5-HT2A receptor activation induces 2-arachidonoylglycerol release through a phospholipase c-dependent mechanism

✍ Scribed by Jason C. Parrish; David E. Nichols

Book ID
111179830
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
206 KB
Volume
99
Category
Article
ISSN
0022-3042

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Modulation of N-methyl-D-aspartate (NMDA) receptor-mediated ion currents by serotonin was investigated with a two-electrode voltage clamp technique in Xenopus oocytes injected with rat brain RNA. After a 1-min application of 200 nM serotonin a transient potentiation of the NMDA receptor-mediated ion