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Serotonin-2A-receptor and -transporter polymorphisms: lack of association in patients with major depression

✍ Scribed by Christo Minov; Thomas C. Baghai; Cornelius Schüle; Peter Zwanzger; Markus J. Schwarz; Peter Zill; Rainer Rupprecht; Brigitta Bondy


Book ID
117471642
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
78 KB
Volume
303
Category
Article
ISSN
0304-3940

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There is evidence indicating that density of 5-HT2A receptors is altered in brain regions of depressed suicide victims and in platelets of suicidal subjects with major depression or schizophrenia. Recent studies have also shown an association between the allele C of 102T/C polymorphism in the 5-HT2A