Seroprevalence Study of Herpes Simplex Virus Type 2 among Pregnant Women in Germany Using a Type-Specific Enzyme Immunoassay

Detection of early antigens in nuclei of

Detection of early antigens in nuclei of cells infected with cytomegalovirus or herpes simplex virus type 1 and 2 by anti-complement immunofluorescence, and use of a blocking assay to demonstrate their specificity

✍ G. Giraldo; E. Beth; U. Hämmerling; G. Tarro; F. M. Kourilsky 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 French ⚖ 975 KB

## Abstract Skin fibroblasts exposed to cytosine arabinoside (Ara C) were infected with either cytomegalovirus (CMV) or herpes simplex virus (HSV) type 1 and 2. Herpesvirus‐determined early antigens (HV‐EA), detected by anti‐complement immunofluorescence (ACIF), occurred primarily in the nuclei, an