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Serological and Clinical Characterization of Anti-dsDNA and Anti-PM/Scl Double-Positive Patients

✍ Scribed by M. MAHLER; E. L. GREIDINGER; M. SZMYRKA; A. KROMMINGA; M. J. FRITZLER

Book ID
111483460
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
107 KB
Volume
1109
Category
Article
ISSN
0890-6564

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## Objective: Anti-pm/scl autoantibodies are found in polymyositis, dermatomyositis, systemic sclerosis (ssc), and systemic autoimmune disease overlap syndromes. pm-1Ξ± is a major epitope of the pm/scl complex, and antibodies against pm-1Ξ± can be detected using a validated enzyme-linked immunosorben