## Abstract To elucidate the roles of human herpesvirus (HHV)β6 and β7 in pregnant women, peripheral blood samples and genital tract secretions were collected serially from pregnant women, and both serological testing and polymerase chain reaction (PCR) were carried out to detect viral DNA in the s
Seroepidemiology of human herpesvirus-6 in pregnant women from different parts of the world
β Scribed by Dr. S. Ranger; S. Patillaud; F. Denis; A. Himmich; A. Sangare; S. M'Boup; A. Itoua-N'Gaporo; M. Prince-David; R. Chout; R. Cevallos; H. Agut
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 524 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0146-6615
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β¦ Synopsis
Abstract
The prevalence of HHVβ6 IgG was studied in 11 different countries across several continents: Morocco, BurkinaβFaso, Congo, Ivory Coast, Mali, Niger, Senegal, Togo, Ecuador, Martinique, and France. The study group consisted of 550 pregnant women, representative of the general adult population in each country. Antibodies were detected by immunofluorescence assay on HSBβ2 cells infected with HHVβ6. Each serum was tested at nine dilutions (1:20 to 1:5,120), sera β₯20 being considered positive. For the HSBβ2 cells. Great differences were seen between separate areas: Morocco showed both low prevalence (20%) and a low geometric mean titer (12), whereas subβSaharan Africa displayed high prevalences (60% to 90%) and variable geometric mean titers (34 to 229). This study revealed a prevalence of 92% for Ecuador, signifcantly higher than the prevalence for Martinique (50%), yet both countries had very low antibody titers compared with those found in Africa. The prevalence in France (76%) was similar to previous results from other European countries.
π SIMILAR VOLUMES
Sera from an epidemiological case-control study of leukaemias and lymphomas conducted between 1980 and 1986 were examined for reactivity to human herpesvirus-6 (HHV-6) by an indirect immunofluorescence assay. Statistical analyses of the data revealed higher HHV-6 seroprevalence and antibody titres i
The presence of human herpesvirus 6 (HHV-6) and human herpesvirus 7 (HHV-7) in throat swabs of 62 children of different age groups (group I, ages &5 month; group II, ages 6-11 months, group 111, ages 12-23 months, group IV, age 2-8 years) and 28 adults was detected by polymerase chain reaction. The