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Serine hydroxymethyltransferase 1 and 2: gene sequence variation and functional genomic characterization

โœ Scribed by Scott J. Hebbring; Yubo Chai; Yuan Ji; Ryan P. Abo; Gregory D. Jenkins; Brooke Fridley; Jianping Zhang; Bruce W. Eckloff; Eric D. Wieben; Richard M. Weinshilboum


Book ID
111184819
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
427 KB
Volume
120
Category
Article
ISSN
0022-3042

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Glycine metabolism inCandida albicans: c
โœ McNeil, J. Bryan; Flynn, Jennifer; Tsao, Nora; Monschau, Nicole; Stahmann, K.-Pe ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 171 KB ๐Ÿ‘ 1 views

Genes encoding the mitochondrial (SHM1) and cytosolic (SHM2) serine hydroxymethyltransferases, and the L-threonine aldolase gene (GLY1) from Candida albicans were cloned and sequenced. All three genes are involved in glycine metabolism. The C. albicans Shm1 protein is 82% identical to that from Sacc