Hepatitis B virus (HBV) infection is the main cause of Controversial data were recently published concerning the fulminant hepatitis (FH) in several geographic areas, includassociation of hepatitis B virus (HBV) variants with fulminant ing the Mediterranean basin. 1 Traditionally the fulminant hepat
Serial studies of pre-S2 and anti-pre-S2 in fulminant hepatitis B
โ Scribed by Martinelli, Pasquale; Maruotti, Giuseppe M.; Oppedisano, Rosamaria; Agangi, Annalisa; Mazzarelli, Laura L.; Votino, Carmela; Quarantelli, Mario; Iaccarino, Vittorio
- Book ID
- 122038546
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 55 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0168-8278
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To determine the time sequence of expression of pre-S2 peptide (1 2C150) during the presymptomatic phase of acute hepatitis B, we used a monoclonal antibody radioimmunoassay in five subjects followed from 30 to 70 days before the onset of liver damage. Pre-S2 peptide was present in serum at low leve
A hybrid cell line producing monoclonal antibodies recognizing an epitope encoded by the pre-(S)2 region of hepatitis B virus (HBV) genome was obtained by fusion of mouse myeloma cells with lymphocytes from mice immunized with HBV. The monoclonal antibody Mo-Fl24 secreted from the hybrid line reacte