Serial liver function tests and percutaneous liver biopsies were performed on 21 children receiving treatment for acute lymphoblastic leukaemia (ALL). The patients received continuing chemotherapy either with daily 6-mercaptopurine and weekly methotrexate or with five-day pulses of these drugs every
Sequential studies on the role of mitoxantrone in the treatment of acute leukaemia
β Scribed by H. G. Prentice; J. Z. Wimperis; G. Robbins
- Publisher
- Springer US
- Year
- 1985
- Tongue
- English
- Weight
- 368 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0167-6997
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Twenty-four patients with acute leukemia or blast crisis (BC) of chronic myelocytic leukemia (CML) in relapse or refractory to standard chemotherapy, were eligible for treatment with mitoxantrone. Mitoxantrone (Novantrone| dihydroxyanthracenedione) was administered in a dose of 8-13 mg/m 2 on five c
## Abstract Clofarabine is a second generation nucleoside analogue. It inhibits DNA repair and activates the mitochondrial apoptotic pathway leading to cell death. __In vitro__ clofarabine has demonstrated synergy with daunorubicin and AraβC and in phase II clinical trials has shown promising activ