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Sequential Roles of Brg, the ATPase Subunit of BAF Chromatin Remodeling Complexes, in Thymocyte Development

✍ Scribed by Tian H. Chi; Mimi Wan; Peggy P. Lee; Koichi Akashi; Daniel Metzger; Pierre Chambon; Christopher B. Wilson; Gerald R. Crabtree


Book ID
117723412
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
972 KB
Volume
19
Category
Article
ISSN
1074-7613

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Brg1, the ATPase subunit of the SWI/SNF
✍ Diana Vradii; Stefan Wagner; Diem N. Doan; Jeffrey A. Nickerson; Martin Montecin πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 406 KB

## Abstract Many mammalian SWI/SNF complexes use Brahma‐related gene 1 (Brg1) as a catalytic subunit to remodel nucleosomes for transcription regulation. In several mesenchymal cells and tissues, expression of a defective Brg1 protein negates the normal activity of the SWI/SNF complex and delays or