Brg1, the ATPase subunit of the SWI/SNF
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Diana Vradii; Stefan Wagner; Diem N. Doan; Jeffrey A. Nickerson; Martin Montecin
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Article
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2005
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John Wiley and Sons
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English
β 406 KB
## Abstract Many mammalian SWI/SNF complexes use Brahmaβrelated gene 1 (Brg1) as a catalytic subunit to remodel nucleosomes for transcription regulation. In several mesenchymal cells and tissues, expression of a defective Brg1 protein negates the normal activity of the SWI/SNF complex and delays or