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Sequential production and activation of matrix-metalloproteinase-9 (MMP-9) with breast cancer progression

✍ Scribed by Sun Young Rha; Joo Hang Kim; Jae Kyung Roh; Kyong Sik Lee; Jin Sik Min; Byung Soo Kim; Hyun Cheol Chung


Book ID
110228412
Publisher
Springer US
Year
1997
Tongue
English
Weight
38 KB
Volume
43
Category
Article
ISSN
0167-6806

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Sequential activation and production of
✍ Kyong Sik Lee; Sun Young Rha; Sea Joong Kim; Joo Hang Kim; Jae Kyong Roh; Byung πŸ“‚ Article πŸ“… 1996 πŸ› Springer 🌐 English βš– 669 KB

The proteolytic processes are thought to be the critical point in tumor invasion and metastasis, mainly by matrix metalloproteinases (MMPs) and serine proteases. We measured the activity of MMP-2 from 28 normal, 12 benign and 126 breast cancer tissues using gelatin zymography. Inactive MMP-2 (72 kD)