Sequential activation and production of
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Kyong Sik Lee; Sun Young Rha; Sea Joong Kim; Joo Hang Kim; Jae Kyong Roh; Byung
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Article
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1996
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Springer
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English
β 669 KB
The proteolytic processes are thought to be the critical point in tumor invasion and metastasis, mainly by matrix metalloproteinases (MMPs) and serine proteases. We measured the activity of MMP-2 from 28 normal, 12 benign and 126 breast cancer tissues using gelatin zymography. Inactive MMP-2 (72 kD)