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Sequential Olefinations on 2-Arylmethylidene-2-phosphonoacetates: A One-Pot Highly Stereoselective Synthesis of 1,2,3-Trisubstituted 1,3-Butadienes.

✍ Scribed by Sonali M. Date; Sunil K. Ghosh


Publisher
John Wiley and Sons
Year
2005
Weight
22 KB
Volume
36
Category
Article
ISSN
0931-7597

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Sequential Double Olefination of 2-(Aryl
✍ Raghunath Chowdhury; Sunil K. Ghosh πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 195 KB

## Abstract An efficient and highly stereoselective synthesis of densely substituted 1,3‐dienes has been achieved which entails a sequential double olefination of 2‐(arylmethylidene)‐2‐phosphonoacetonitriles by a one‐pot domino process involving Michael addition of dimsyllithium to 2‐(arylmethylide