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Sequential Metal Binding by the RING Finger Domain of BRCA1 †

✍ Scribed by Roehm, Pamela C.; Berg, Jeremy M.

Book ID
126959951
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
160 KB
Volume
36
Category
Article
ISSN
0006-2960

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## Abstract BARD1 (BRCA1‐associated RING domain) was identified by yeast two‐hybrid screening as a protein interacting with BRCA1. Somatic and germline mutations of __BARD1__ have been detected in sporadic breast, ovarian, and endometrial cancers. The present study represents the first description