โ Scribed by Wiktor, Anne; Puskorius, Regina; Zubrickas, Kristina; Van Dyke, Daniel L.
No coin nor oath required. For personal study only.
We describe a method for fluorescent in situ hybridization (FISH) on previously Gbanded slides and mounted coverslip preparations. The technique is successful on previously G-banded slides from peripheral blood and bone marrow specimens and on amniotic fluid samples from in situ harvests. Satellite sequence probes, whole chromosome paints, and unique sequence probes have all produced reliable results.
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Only a few cases of de novo complex chromosome rearrangements (CCRs) in amniotic fluid have been reported [
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