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Sequential exposure of Aspergillus fumigatus to itraconazole and caspofungin: evidence of enhanced in vitro activity

โœ Scribed by Dimitrios P. Kontoyiannis; Russell E. Lewis; Michail S. Lionakis; Nathaniel D. Albert; Gregory S. May; Issam I. Raad


Book ID
117559388
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
204 KB
Volume
47
Category
Article
ISSN
0732-8893

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The purpose of this study was to assess the antifungal activity, pharmacokinetics, and tissue distribution of amphotericin B (AmpB) following the administration of Abelcet and AmBisome alone and in combination with Caspofungin to rats infected with Aspergillus fumigatus. Aspergillus fumigatus inocul