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Sequential activation of MAP kinase cascade by angiotensin II in opossum kidney cells

✍ Scribed by Terada, Yoshio; Tomita, Kimio; Homma, Miwako K; Nonoguchi, Hiroshi; Yang, Tianxin; Yamada, Takehisa; Yuasa, Yasuhiro; Krebs, Edwin G; Marumo, Fumiaki


Book ID
109884246
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
868 KB
Volume
48
Category
Article
ISSN
0085-2538

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Stimulation of Na+/H+exchange activity b
✍ R. Walter; C. Helmle-Kolb; J. Forgo; U. Binswanger; H. Murer πŸ“‚ Article πŸ“… 1995 πŸ› Springer 🌐 English βš– 931 KB

Endothelin-1 (ET-1) controls multiple aspects of kidney function. In this study we have analysed the effects of ET-1 on apical Na+/H + exchange activity in opossum kidney (OK) cells. ET-1 (at 10-1~ and 10-SM) activated Na+/H + exchange activity within 5 min of exposure. ET-1 (10 -8 M) prevented PTHi