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Sequence variations in DNA repair geneXPCis associated with lung cancer risk in a Chinese population: a case-control study

✍ Scribed by Yun Bai; Liang Xu; Xiaobo Yang; Zhibin Hu; Jing Yuan; Feng Wang; Minhua Shao; Wentao Yuan; Ji Qian; Hongxia Ma; Ying Wang; Hongliang Liu; Weihong Chen; Lin Yang; Guangfu Jing; Xiang Huo; Feng Chen; Yanhong Liu; Li Jin; Qingyi Wei; Wei Huang; Hongbing Shen; Daru Lu; Tangchun Wu

Book ID
115011150
Publisher
BioMed Central
Year
2007
Tongue
English
Weight
295 KB
Volume
7
Category
Article
ISSN
1471-2407

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Sequence variations in the DNA repair ge
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## Abstract Variation in DNA repair capacity, which is believed to be largely determined by genetic traits, is linked to risk of certain cancers. The Asp312Asn and Lys751Gln polymorphisms in the xeroderma pigmentosum complementary group D (XPD) gene may alter DNA repair capacity. We thus examined t

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## Abstract DNA repair is central to normal cellular functions, and polymorphisms of DNA repair genes may cause variation in DNA repair capacity in the general population. Newly identified polymorphisms of xeroderma pigmentosum group C (__XPC__), one of the nucleotide excision repair genes, were sh