Sequence variability of the tetranucleotide repeat of the human beta-actin related pseudogene H-beta-Ac-psi-2 (ACTBP2) locus

✍ Scribed by Andy Urquhart; Colin P. Kimpton; Peter Gill

• Book ID: 104769058
• Publisher: Springer
• Year: 1993
• Tongue: English
• Weight: 126 KB
• Volume: 92
• Category: Article
• ISSN: 0340-6717
• DOI: 10.1007/bf00420957

✦ Synopsis

Sequence analysis of polymerase chain reaction (PCR) amplified products from the presumed tetranucleotide repeat at the human beta-actin related pseudogene H-beta-Ac-psi-2 (ACTBP2) locus shows far greater variability in both PCR product length and sequence than has been previously reported. Alleles differing in size by 1 bp exist, and accurate sizing is required if the locus is to be used to its full potential.