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Sequence-Tagged NotI Sites of Human Chromosome 21: Sequence Analysis and Mapping

โœ Scribed by Masahira Hattori; Atushi Toyoda; Hitoshi Ichikawa; Takashi Ito; Hideko Ohgusu; Nobue Oishi; Takeshi Kano; Satoru Kuhara; Misao Ohki; Yoshiyuki Sakaki


Book ID
115611650
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
374 KB
Volume
17
Category
Article
ISSN
0888-7543

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The transcription start sites of many genes are associated with CpG-rich DNA regions (CpG islands) containing clusters of rare cutting, methylation-sensitive restriction enzyme sites [Bird, 1986]. To detect gene sequences from human chromosome 21, we have screened cloned DNA fragments from a chromos