Sequence-specific chemical modification
โ
V. V. Vlassov; N. D. Kobetz; E. L. Chernolovskaya; S. G. Demidova; R. G. Borisso
๐
Article
๐
1990
๐
Springer
๐
English
โ 301 KB
Chemical modification of the chromatin DNA with alkylating derivatives of oligothymidylate (pT)16 and oligoadenylate (pA)16 bearing 4-(N-2-chloroethyl-N-methylamino)benzylphosphamide group at the 5'-phosphate has been investigated. It was found that the derivatives do react with DNA in chromatin. Th