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Sequence-specific bacterial growth inhibition by peptide nucleic acid targeted to the mRNA binding site of 16S rRNA

✍ Scribed by Masashi Hatamoto; Kazufumi Nakai; Akiyoshi Ohashi; Hiroyuki Imachi

Book ID
105952165
Publisher
Springer
Year
2009
Tongue
English
Weight
246 KB
Volume
84
Category
Article
ISSN
1432-0614

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Inhibition of bacterial translation and growth by peptide nucleic acids targeted to domain II of 23S rRNA
✍ Huang Xue-Wen; Pan Jie; An Xian-Yuan; Zhuge Hong-Xiang 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 224 KB

## Abstract The objective of this work was to study the inhibitory effects of antisense peptide nucleic acids (PNAs) targeted to domain II of 23S rRNA on bacterial translation and growth. In this paper, we report that PNA(G1138) or peptide‐PNA(G1138) targeted to domain II of 23S rRNA can inhibit bo