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Sequence polymorphisms of the mtDNA control region in a human isolate: the Georgians from Swanetia

✍ Scribed by Miguel A. Alfonso-Sánchez; Cristina Martínez-Bouzas; Azucena Castro; Jose A. Peña; Isabel Fernández-Fernández; Rene J. Herrera; Marian M. de Pancorbo


Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
318 KB
Volume
51
Category
Article
ISSN
1435-232X

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The mitochondrial DNA (mtDNA) control region is believed to play an important biological role in mtDNA replication. Large deletions in this region are rarely found, but when they do occur they might be expected to interfere with the replication of the molecule, thus leading to a reduction of mtDNA c