## Abstract Human complement factorβ H (factorβ H) is polymorphic, with five previously reported FH alleles and three previously reported HF alleles (HF\*A, HF\*B, and HF\*Q0). The relationship between the FH and HF alleles is not clear, and the genetic basis of factorβ H phenotypes has not yet been i
Sequence polymorphism of human complement factor H
β Scribed by Anthony J. Day; Antony C. Willis; Jean Ripoche; Robert B. Sim
- Publisher
- Springer-Verlag
- Year
- 1988
- Tongue
- English
- Weight
- 305 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0093-7711
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
An assessment has been made of the polymorphism of human complement component C4 by comparing derived amino acid sequences of cDNA and genomic DNA with limited amino acid sequences. In all, one complete and six partial sequences have been obtained from material from three individuals and include two
Age-related macular degeneration (AMD) is the most common cause of irreversible visual loss in the developed world. Previous studies have demonstrated that the c.1204T>C, p.Tyr402His allelic variant in the complement factor H (CFH) gene is associated with an approximately three-fold increased risk f