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Sequence of alterations in subcellular organelles during the development of heart dysfunction in diabetes

✍ Scribed by Nobuakira Takeda; Ian M.C. Dixon; Tornoji Hata; Vijayan Elimban; Kanu R. Shah; Naranjan S. Dhalla

Book ID
119525413
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
701 KB
Volume
30
Category
Article
ISSN
0168-8227

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Alterations in Ca2+-channels during the
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In order to examine the status of Ca2+ channels in heart sarcolemma during the development of diabetes, rats were injected intravenously with 65 mg/kg streptozotocin and hearts were removed 1, 3 and 8 weeks later. Crude membranes from the ventricular muscle were prepared and the specific binding of