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Sequence-Independent Recombination Triple Helices: A Molecular Dynamics Study

✍ Scribed by Kiran, M. Ravi; Bansal, Manju

Book ID
127379465
Publisher
Adenine Press
Year
1997
Tongue
English
Weight
896 KB
Volume
15
Category
Article
ISSN
0739-1102

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## Abstract Phosphorothioate oligonucleotides (PS–ODNs) have gained considerable attention in drug therapy, primarily as potent antisense or antigene oligomers, which bind to specific DNA or mRNA sequences and lead to transcriptional or translational arrest. These are obtained by substituting one o