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Sequence homology and structural comparison between the chromosomal human α1-antitrypsin and chicken ovalbumin genes

✍ Scribed by Mace, Myles; Davie, Earl W.; Woo, Savio L. C.; Leicht, Margaret; Long, George L.; Chandra, T.; Kurachi, Kotoku; Kidd, Vincent J.

Book ID
109726741
Publisher
Nature Publishing Group
Year
1982
Tongue
English
Weight
845 KB
Volume
297
Category
Article
ISSN
0028-0836

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From family studies close linkage between the gene locus for variegate porphyria (VP) and the alpha-1-antitrypsin (PI) gene became evident. The maximal lod score from male meioses was 4.33 at theta = 0.04 and from both sexes combined 3.56 at theta = 0.12. Three pedigrees were triple informative rega