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Sequence-dependence and prediction of nucleotide solvent accessibility in double stranded DNA

✍ Scribed by Shandar Ahmad

Book ID: 116508156
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 778 KB
Volume: 428
Category: Article
ISSN: 0378-1119
DOI: 10.1016/j.gene.2008.09.031

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## Abstract The effect of exposure of guanine in double‐stranded oligonucleotides to aqueous solvent during oxidation by one‐electron oxidants was investigated by introducing single synthetic tetrahydrofuran‐type abasic sites (__Ab__) either adjacent to or opposite tandem GG sequences. The selectiv