Sequence Conservation of Human Cytomegalovirus UL140 Open Reading Frame in Clinical Strains
โ Scribed by Ying Qi; Yan-ping Ma; Rong He; Zheng-rong Sun; Yao-hua Ji; Yu-jing Huang; Qiang Ruan
- Book ID
- 117692189
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 456 KB
- Volume
- 23
- Category
- Article
- ISSN
- 1001-9294
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๐ SIMILAR VOLUMES
Human cytomegalovirus (HCMV) infects a number of organs and cell types, leading to the hypothesis that HCMV disease and tissue tropism may be related to specific sequence variability. This study examined the genomic variability of a new polymorphic locus in HCMV, UL139 open reading frame (ORF). Deta
## Abstract Human cytomegalovirus (HCMV) is a ubiquitous pathogen that infects a variety of cell types in vivo. A region (referred to as UL/b') present in the Toledo strain of HCMV and low passage clinical isolates contains 22 additional genes, which are absent in the highly passaged laboratory str