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Sequence and Temperature Dependence of the End-to-End Collision Dynamics of Single-Stranded DNA

✍ Scribed by Uzawa, Takanori; Isoshima, Takashi; Ito, Yoshihiro; Ishimori, Koichiro; Makarov, Dmitrii E.; Plaxco, Kevin W.

Book ID
121703151
Publisher
Biophysical Society
Year
2013
Tongue
English
Weight
726 KB
Volume
104
Category
Article
ISSN
0006-3495

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## Abstract ## Background Single‐stranded oligonucleotides (ssODN) can induce site‐specific genetic alterations in selected mammalian cells, but the involved mechanisms are not known. ## Methods We corroborate the potential of genomic sequence correction by ssODN using chromosomally integrated m