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Sequence and promoter regulation of the PCK1 gene encoding phosphoenolpyruvate carboxykinase of the fungal pathogen Candida albicans

✍ Scribed by Christoph E Leuker; Anja Sonneborn; Sebastian Delbrück; Joachim F Ernst


Book ID
117522355
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
491 KB
Volume
192
Category
Article
ISSN
0378-1119

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The KlPCK1 gene encoding phosphoenolpyruvate carboxykinase (PEPCK; ATP-dependent) was cloned from the Kluyveromyces lactis genome using a PCR amplicon from Saccharomyces cerevisiae PCK1 gene as a probe. A DNA fragment of about 4•8 kb containing KlPCK1 complemented PEPCK activity of the mutant of S.