Sequence and expression of the rainbow trout winged helix/forkhead transcription factor FoxF1
โ Scribed by Yoshie Hidaka; Shigeyasu Tanaka; Masakazu Suzuki
- Book ID
- 113802227
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 745 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1567-133X
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## Abstract Summary: Satin (__sa__) homozygous mice have a silky coat with high sheen arising from structurally abnormal medulla cells and defects in differentiation of the hair shaft. We demonstrate that the winged helix/forkhead transcription factor, __Foxq1__ (Forkhead box, subclass __q____,__ m
The molecular characteristics of the nude phenotype (alopecia and thymic aplasia) in humans and rodents are unknown. The nude locus encodes Whn, a transcription factor of the forkhead/winged-helix class. Expression of Whn in HeLa cells induced expression of human hair keratin genes Ha3-II and Hb5. C