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Sequence and developmental expression of amphioxusAmphiNk2–1: insights into the evolutionary origin of the vertebrate thyroid gland and forebrain

✍ Scribed by T. V. Venkatesh; Nicholas D. Holland; Linda Z. Holland; Ming-Tsan Su; Rolf Bodmer


Publisher
Springer-Verlag
Year
1999
Tongue
English
Weight
200 KB
Volume
209
Category
Article
ISSN
0949-944X

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## Abstract Summary: The __Thyroid transcription factor‐1 (TTF‐1)__ gene belongs to the __Nkx‐2.1__ subfamily and encodes a transcription factor containing an NK‐2‐type homeodomain. In our study, we isolated and characterized cDNA clones for the __TTF‐1/Nkx‐2.1__ orthologue __(LjTTF‐1)__ from the a