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Sequence Analysis of the MYC Oncogene Involved in the t(8;14)(q24;q11) Chromosome Translocation in a Human Leukemia T-Cell Line Indicates that Putative Regulatory Regions are not Altered

✍ Scribed by Sheldon N. Finver, Kazuko Nishikura, Lawrence R. Finger, Frank G. Haluska, Janet Finan, Peter C. Nowell and Carlo M. Croce

Book ID: 123635752
Publisher: National Academy of Sciences
Year: 1988
Tongue: English
Weight: 988 KB
Volume: 85
Category: Article
ISSN: 0027-8424
DOI: 10.2307/31942

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An (8;14)(q24;q11) translocation involving the T-cell receptor α-chain gene and the MYC oncogene 3′ region in a B-cell lymphoma

✍ James K. Park; Timothy W. McKeithan; Michelle M. le Beau; Mitchell A. Bitter; Wi 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 796 KB

We describe a t(8; I4)(q24;q I I) involving the T-cell receptor a-chain gene (TCRA) and the 3' region of the MYC protooncogene in a B-cell lymphoma. The 6-cell origin of this tumor was determined by its histological architecture, by immunophenotypic analysis, and by Southern analysis of immunoglobul