Lethal mutations in the structural gene
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Freudl, Roland ;Braun, Gabi ;Hindennach, Ingrid ;Henning, Ulf
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Article
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1985
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Springer
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English
⚖ 786 KB
The gene ompA encodes a major outer membrane protein of Escherichia coli. Localized mutagenesis of the part of the gene corresponding to the 21-residue signal sequence and the first 45 residues of the protein resulted in alterations which caused cell lysis when expressed. DNA sequence analyses revea