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Sequence analysis of mutations that prevent export of λ receptor, an Escherichia coli outer membrane protein

✍ Scribed by Emr, Scott D.; Hedgpeth, Joe; Clément, Jean-Marie; Silhavy, Thomas J.; Hofnung, Maurice


Book ID
109718508
Publisher
Nature Publishing Group
Year
1980
Tongue
English
Weight
439 KB
Volume
285
Category
Article
ISSN
0028-0836

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The gene ompA encodes a major outer membrane protein of Escherichia coli. Localized mutagenesis of the part of the gene corresponding to the 21-residue signal sequence and the first 45 residues of the protein resulted in alterations which caused cell lysis when expressed. DNA sequence analyses revea