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Sequence analysis of a radiation-induced deletion breakpoint fusion in mouse

✍ Scribed by J. W. Thomas; B. C. Holdener; T. Magnuson

Book ID
104744126
Publisher
Springer-Verlag
Year
1994
Tongue
English
Weight
116 KB
Volume
5
Category
Article
ISSN
0938-8990

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✦ Synopsis

C llDSD is an X-ray-induced deletion generated at the Oak Ridge National Laboratory (Russell et al. 1979) that spans ~3 cM (Sharan et al. 1991) of mouse Chromosome (Chr)

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## Abstract Gamma radiation–induced gene rearrangements at the Chinese hamster ovary cell locus coding for the purine salvage enzyme adenine phosphoribosyl transferase (APRT) consist of both simple deletions and more complex alterations that are presumably the result of multiple strand breaks. To c