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Sequence analysis of a partial deletion of the human steroid sulfatase gene reveals 3 bp of homology at deletion breakpoints

✍ Scribed by Bernatowicz, Lynne F.; Li, Xiao-Miao; Carrozzo, Romeo; Ballabio, Andrea; Mohandas, Thuluvancheri; Yen, Pauline H.; Shapiro, Larry J.


Book ID
123264296
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
275 KB
Volume
13
Category
Article
ISSN
0888-7543

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## Abstract Homozygous deletions or loss of heterozygosity (LOH) at human chromosome band 3p12 are consistent features of lung and other malignancies, suggesting the presence of a tumor suppressor gene(s) (TSG) at this location. Only one gene has been cloned thus far from the overlapping region del