Separation Techniques in Clinical Chemistry

✍ Scribed by Hassan Y. Aboul-Enein

Publisher: CRC Press
Year: 2003
Tongue: English
Leaves: 523
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

This reference examines innovations in separation science for improved sensitivity and cost-efficiency, increased speed, higher sample throughput and lower solvent consumption in the assessment, evaluation, and validation of emerging drug compounds. It investigates breakthroughs in sample pretreatment, HPLC, mass spectrometry, capillary electrophoresis and therapeutic drug monitoring for improved productivity, precision, and safety in clinical chemistry, biomedical analysis, and forensic research.From saliva, hair, and biological samples to illegal drugs and toxins, Separation Techniques in Clinical Chemistry is a thorough single-source guide for analytical, organic, pharmaceutical, medicinal, physical, surface, and colloid chemists and biochemists; and upper-level undergraduate and graduate students in these disciplines.

✦ Table of Contents

Preface......Page 4
Contents......Page 6
Ch. 1 Sample Pretreatment in Clinical Chemistry......Page 10
Ch. 2 Separation Science in Therapeutic Drug Monitoring......Page 112
Ch. 3 The Impact of Chirality in Pharmacokinetics and Therapeutic Drug Monitoring......Page 147
Ch. 4 HPLC in Bioavailability Examination......Page 170
Ch. 5 Validation of HPLC Analyses in Therapeutic Drug Monitoring......Page 199
Ch. 6 Analysis of Illicit Drugs with Chromatographic Methods......Page 227
Ch. 7 Biogenic Amine Neurotransmitters: Their Importance and Measurement in Human Tissue and Body Fluids......Page 295
Ch. 8 Clinical Applications of Affinity Chromatography......Page 327
Ch. 9 Immunoaffinity Chromatography in Clinical Analysis......Page 366
Ch. 10 Electrospray Tandem Mass Spectrometry in the Biochemical Genetics Laboratory......Page 393
Ch. 11 Application of Thin-Layer Chromatography in Clinical Chemistry......Page 437
Ch. 12 Applications of Capillary Electrophoresis in Clinical Analysis of Drugs......Page 492

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