Separation of thiodiglycol polyethers and related compounds by reversed-phase high-performance liquid chromatography

✍ Scribed by Douglas E. Doster; Melodee Zentner

• Publisher: Elsevier Science
• Year: 1989
• Tongue: English
• Weight: 591 KB
• Volume: 461
• Category: Article
• ISSN: 1873-3778
• DOI: 10.1016/s0021-9673(00)94296-1

✦ Synopsis

Low-molecular-weight (MW < 3000) thiodiglycolpolyether polymers were separated by reversed-phase high-performance liquid chromatography into as many as twenty oligomeric species. This separation was accomplished by using gradient elution with water and methanol on a semi-microbore ODS reversed-phase column. Detection was by the use of a diode-array UV detector. The method was also used in the separation of sulfur-containing cyclic compounds, polysulfur thiodiglycol compounds and polythiodiglycol formal oligomers. The separation of these compounds provides data that indicate that the separation mechanism for the thiodiglycolpolyether polymers is a combination of precipitation dissolution and sorption mechanisms. Structural proof of the polysulfur thiodiglycol compounds was obtained by NMR.