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Separation of the pore-forming and cytotoxic activities from natural killer cell cytotoxic factor

✍ Scribed by L.P. Sashchenko; N.V. Gnuchev; M.A. Kirillova; T.I. Lukjanova; T.V. Rebizova; E.S. Revazova; E.M. Lukanidin

Book ID
115921421
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
303 KB
Volume
226
Category
Article
ISSN
0014-5793

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## Abstract The effect of actinomycin D on target susceptibility to human blood natural killer (NK) cells and monocytes was analysed in direct cell‐mediated and their cytotoxic factor‐mediated cytotoxicity assays. Treatment of K562 cells with actinomycin D reduced their susceptibility to lysis by n