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Separation of tetracycline and its related substances: comparison of liquid chromatography, capillary electrophoresis and capillary electrochromatography

✍ Scribed by J. Saevels; M. Wuyts; A. Van Schepdael; E. Roets; J. Hoogmartens

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
67 KB
Volume
12
Category
Article
ISSN
0269-3879

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The enantiomers of ␣-phosphonosulfonic acids were completely resolved by capillary electrophoresis using ␀-cyclodextrin as a chiral selector in a borate electrolyte and by HPLC using a chiral AGP column. The methods were used to quantitate the R-enantiomer present as an impurity in the S-enantiomer,