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Separation of retinoblastoma and esterase D loci in a patient with sporadic retinoblastoma and del(13)(q14.1q22.3)

✍ Scribed by Robert S. Sparkes; Maryellen C. Sparkes; Robert E. Kalina; Roberta A. Pagon; Darrell J. Salk; Christine M. Disteche

Publisher: Springer
Year: 1984
Tongue: English
Weight: 229 KB
Volume: 68
Category: Article
ISSN: 0340-6717
DOI: 10.1007/bf00418397

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✦ Synopsis

A chromosome 13 deletion in a patient with sporadic retinoblastoma appears to have separated the loci for retinoblastoma and esterase D. This study indicates that: (1) the retinoblastoma locus is distinct from the esterase D locus; and (2) the linear order of these genes is centromere-esterase D-retinoblastoma.

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