Determination of the enantiomers of α-H-
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A. Duchateau; M. Crombach; J. Kamphuis; W.H.J. Boesten; H.E. Schoemaker; E.M. Me
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Article
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1989
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Elsevier Science
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English
⚖ 526 KB
o-Phthalaldehyde in combination with N-acetyl-L-cysteine is a useful derivatization reagent for the optical resolution of enantiomeric a-H-a-amino acids, a-alkyl-a-amino acids and the corresponding acid amides. By using reversed-phase high-performance liquid chromatography with a mobile phase contai