Separation of racemic bupivacaine using Simulated Moving Bed with mathematical model
β Scribed by Young Jae Choi; Soon Koo Han; Sung Taik Chung; Kyung Ho Row
- Publisher
- The Korean Society for Biotechnology and Bioengineering
- Year
- 2007
- Tongue
- English
- Weight
- 597 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1226-8372
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## Abstract Simulated moving bed (SMB) processes have been widely used in the sugar industries with ionβexchange resin as a stationary phase. DβPsicose, a rare monosaccharide known as a valuable pharmaceutical substrate, was synthesized by the enzymatic conversion from Dβfructose. The SMB process w
In a previous publication, an algebraic solution of Simulated Moving-Bed (SMB) chromatography was derived in the linear, ideal case for a binary mixture. This solution predicts the concentration profiles of the two components along the columns and the concentration histories at the raffinate and the