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Separation of oligonucleotides with single-base mutation by capillary electrophoresis using specific interaction of metal ion with nucleotide

✍ Scribed by Takahashi, Toru; Sakurai, Takao; Hirata, Koichiro; Hoshino, Hitoshi


Book ID
111964401
Publisher
Royal Society of Chemistry
Year
2009
Tongue
English
Weight
141 KB
Volume
134
Category
Article
ISSN
0003-2654

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## Abstract The interactions between tetranucleotides or heptanucleotides and inorganic cations have been measured by affinity CZE. The variation in migration behavior with increasing concentrations of divalent cations (Ca^2+^, Mg^2+^ and Ni^2+^) in the running buffer was investigated and quantifie