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Separation of Endosulphan and its Major Metabolites by GC and HPLC

✍ Scribed by Inderjeet Kaur; Ashesh Kumar; P. Duraja

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
217 KB
Volume
11
Category
Article
ISSN
0269-3879

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✦ Synopsis

sulphan (technical) was obtained from Excel, Bangalore (India) Limited. Endosulphan I and II were separated from technical endosulphan (70 : 30) by column chromatography and purified by crystallization, and endosulphan sulphate, endosulphan ether, endosulphan diol and endosulphan lactone were prepared by methods described in the literature. The purity of all the metabolites was checked by GLC and found to be 99%. All solvents were degassed by simultaneous warming (gently) and evacuation for 15 min. Double distilled water was filtered through a Millipore assembly with filters of 0.45 m porosity, solvent compatible and degassed before use for HPLC.

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