Separation of acetic and propionic acid analogs of l-thyroxine and l-triiodothyronine by thin-layer chromatography

✍ Scribed by S. Naidoo

• Publisher: Elsevier Science
• Year: 1978
• Tongue: English
• Weight: 266 KB
• Volume: 91
• Category: Article
• ISSN: 0003-2697
• DOI: 10.1016/0003-2697(78)90541-9

✦ Synopsis

A thin-layer chromatographic method is described for the separation of the acetic and propionic acid analogs of thyroxine and triiodothyronine, which are inseparable by currently available methods. The separation is achieved on silica gel H in a solvent system consisting of methylacetate-2.5% ammonia (w/v) (95:5 v/v). The complete analysis takes 2 h.