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Separation, identification and assay of fluradoline hydrochloride in the presence of other tricyclic antidepressants or neuroleptics by spectra and thin-layer and liquid chromatographic methods

✍ Scribed by J. Joseph-Charles; M. Bertucat


Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
590 KB
Volume
284
Category
Article
ISSN
0003-2670

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✦ Synopsis


AbStIWt

Phtradobne hydrochloride is a novel centrally acting analgesic with antidepressant activity. Its W absorption and emission spectra and thin-layer and liquid chromatographic (TLC and LC) identification are described. The separation of tricyclic antidepressant or neuroleptic compounds including zotepine, amoxapine, loxapine, fluperlapine, clotiapine, nitroxaze pine and fluradoline by TLC and LC is reported. The W spectrophotometric, spectrofluorimetric and LC methods described can be applied to the determination of fluradoline.