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Separation and structure determination of nicardipine photoproducts by LC-ESI-MS

✍ Scribed by Shih-Ming Chen; Mau-Chih Hsieh; Su-Hui Chao; E. E. Chang; Po-Yu Wang; An-Bang Wu


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
234 KB
Volume
22
Category
Article
ISSN
0269-3879

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A rapid, accurate and reliable reversed-phase high-performance liquid chromatographic (HPLC) method for the determination of naproxen and its photodegradation products in methanol was developed and validated. An Inertsil 5-ODS-3V column (5 microm, C18, 250 x 4.6 mm i.d.) was used with a mobile phase