The objectives of this study were to determine whether submicron-sized ultra-high-molecular-weight polyethylene (UHMWPE) wear debris was present in synovial fluid surrounding knee implants, and to report on the utility of a light-scattering technique for the in situ analysis of submicron-sized wear
Separation and characterization of polyethylene wear debris from synovial fluid and tissue samples of revised knee replacements
✍ Scribed by Wolfarth, Debra L. ;Han, David W. ;Bushar, Grace ;Parks, Nancy L.
- Book ID
- 101255016
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 351 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0021-9304
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✦ Synopsis
A study was made of in vivo-generated polyethylene wear par-
The particles of the same size range found in the synovial ticles as separated from synovial fluid samples and from tissue fluid and tissue samples exhibited a comparable morpholsamples surrounding total knee arthroplasty. A comparison ogy. Notably, submicron-sized debris was present in both of particle size and morphology between the two particle the synovial fluid and tissue samples surrounding knees with groups was made to assess any effects of selective tissue cap-osteolysis. The novel micro-Raman analysis of individual ture, and macrophage encapsulation and digestion. In addi-particles was successful in the categorizing of wear debris as tion, a Raman spectroscopy technique was evaluated that en-polyethylene or nonpolyethylene. ᭧ 1997 John Wiley & Sons, Inc. ables positive identification of individual wear particles.
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