Sensory neuropathy in infantile onset spinocerebellar ataxia (IOSCA)
β Scribed by Dr. Tuula Koskinen; Dr. Kimmo Sainio; Dr. Juhani Rapola; Dr. Helena Pihko; Dr. Anders Paetau
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 668 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0148-639X
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## Abstract In dominant spinocerebellar ataxias (SCAs), the issue of whether nonβCAG dependent factors contribute to onset age remains unsettled. Data on SCA genotype, onset age, normal/expanded CAG repeat length, sex of the patient and transmitting parent, and family details were available from 80
We studied a seven-generation kindred with autosomal dominant spinocerebellar ataxia (SCA) to assess linkage relationships to multiple human leukocyte antigen (HLA) loci on the short arm of chromosome 6. Age at onset, clinical features, and course of the disease are described. Although the mean age